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nickel cofactor biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
deamido-NAD+ + HCO3- <=> pyridin-1-ium-3,5-dicarboxylate_mononucleotide + AMP + H+ 2.5.1.143 pyridinium-3,5-biscarboxylic acid mononucleotide synthase

[LarE]-L-cysteine + 1-(5-O-phospho-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium-3-carbonyl_adenylate <=> [LarE]-S-[1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium-3-carbonyl]-L-cysteine + AMP + H+ 4.4.1.37 pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase

ATP + pyridin-1-ium-3-carboxylate-5-thiocarboxylate_mononucleotide + H+ <=> 1-(5-O-phospho-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium-3-carbonyl_adenylate + diphosphate 4.4.1.37 pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase

[LarE]-L-cysteine + 5-carboxy-1-(5-O-phospho-beta-D-ribofuranosyl)pyridin-1-ium-3-carbonyl_adenylate <=> [LarE]-S-[5-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridin-1-ium-3-carbonyl]-L-cysteine + AMP + H+ 4.4.1.37 pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase

ATP + pyridin-1-ium-3,5-dicarboxylate_mononucleotide + H+ <=> diphosphate + 5-carboxy-1-(5-O-phospho-beta-D-ribofuranosyl)pyridin-1-ium-3-carbonyl_adenylate 4.4.1.37 pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase

[LarE]-S-[5-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridin-1-ium-3-carbonyl]-L-cysteine <=> [LarE]-dehydroalanine + pyridin-1-ium-3-carboxylate-5-thiocarboxylate_mononucleotide 4.4.1.37 pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase

[LarE]-S-[1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium-3-carbonyl]-L-cysteine <=> [LarE]-dehydroalanine + pyridinium-3,5-bisthiocarboxylate_mononucleotide 4.4.1.37 pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase

pyridin-1-ium-3-thioamide-5-thiocarboxylate_mononucleotide_Ni_pincer_complex + H+ <=> Ni2+ + pyridinium-3,5-bisthiocarboxylate_mononucleotide 4.99.1.12 pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel chelatase

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